The short version
- Grades describe severity in a shared vocabulary.
- Mild, moderate and severe have specific research meanings.
- A grade does not by itself prove the product caused the event.
Shared scales
Many studies use published grading criteria so that “moderate” means roughly the same thing across sites.
What changes with grade
Higher grades may trigger more reporting, dose changes or extra visits, according to the protocol.
Relatedness is separate
Teams also judge whether an event seems related to the study product. That judgment is separate from the grade.
Reading a results table
When you see graded events in a summary, look for which grades were common and how many people stopped.
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